We are very pleased that we will be hosting ISNI 2025 in Japan next October. After COVID-19, our daily life as well as academic activities changed drastically: to prevent spreading of infection, virtual meetings have tended to be preferred so we lost many opportunities for building connections and scientific discourse through social interactions with wine and feasting. However, the trend has now clearly changed. In Japan, we are now seeing many more tourists than before COVID-19, and station platforms of the Shinkansen bullet train are crowded with foreign tourists. This seems to be like a rebound phenomenon after withdrawal of immunosuppressive treatments!